Abstract
This report examines in detail a family of efficacy-toxicity trade-off functions simpler and more general than those originally proposed in [1]. The new trade-off functions are based on distance in Lp norm to the ideal point and were first presented in [2]. We define and illustrate these functions and demonstrate how to compute their parameters based on elicited values.
Disciplines
Statistical Methodology | Statistical Theory
Suggested Citation
Cook, John D., "Efficacy-Toxicity trade-offs based on Lp norms" (December 2006). UT MD Anderson Cancer Center Department of Biostatistics Working Paper Series. Working Paper 29.
http://biostats.bepress.com/mdandersonbiostat/paper29