#### Abstract

The attributable risk, often called the population attributable risk, is in many epidemiological contexts a more relevant measure of exposure-disease association than the excess risk, relative risk, or odds ratio. When estimating attributable risk with case-control data and a rare disease, we present a simple correction to the standard approach making it essentially unbiased, and also less noisy. As with analogous corrections given in Jewell (1986) for other measures of association, the adjustment often won't make a substantial difference unless the sample size is very small or point estimates are desired within fine strata, but we discuss the possible utility for applications.

#### Disciplines

Biostatistics | Categorical Data Analysis | Epidemiology | Statistical Methodology | Statistical Theory

#### Suggested Citation

Rubin, Daniel B., "A Small Sample Correction for Estimating Attributable Risk in Case-Control Studies" (December 2008). *U.C. Berkeley Division of Biostatistics Working Paper Series.* Working Paper 243.

http://biostats.bepress.com/ucbbiostat/paper243

#### Included in

Biostatistics Commons, Categorical Data Analysis Commons, Epidemiology Commons, Statistical Methodology Commons, Statistical Theory Commons