Title
Marginalized Transition Models for Longitudinal Binary Data With Ignorable and Nonignorable Dropout
Abstract
We extend the marginalized transition model of Heagerty (2002) to accommodate nonignorable monotone dropout. Using a selection model, weakly identified dropout parameters are held constant and their effects evaluated through sensitivity analysis. For data missing at random (MAR), efficiency of inverse probability of censoring weighted generalized estimating equations (IPCW-GEE) is as low as 40% compared to a likelihood-based marginalized transition model (MTM) with comparable modeling burden. MTM and IPCW-GEE regression parameters both display misspecification bias for MAR and nonignorable missing data, and both reduce bias noticeably by improving model fit
Disciplines
Categorical Data Analysis | Design of Experiments and Sample Surveys | Longitudinal Data Analysis and Time Series | Statistical Models
Suggested Citation
Kurland, Brenda F. and Heagerty, Patrick J., "Marginalized Transition Models for Longitudinal Binary Data With Ignorable and Nonignorable Dropout" (December 2003). UW Biostatistics Working Paper Series. Working Paper 222.
https://biostats.bepress.com/uwbiostat/paper222
Included in
Categorical Data Analysis Commons, Design of Experiments and Sample Surveys Commons, Longitudinal Data Analysis and Time Series Commons, Statistical Models Commons
Comments
This paper has been published, and the new reference is: Kurland, B.F. and Heagerty, P. J. (2004) Marginalized transition models for longitudinal binary data with ignorable and non-ignorable drop-out. Statistics in Medicine, 23(17), 2673-2695. http://www3.interscience.wiley.com/cgi-bin/jissue/109593835