As an epidemiological parameter, the population attributable fraction is an important measure to quantify the public health attributable risk of an exposure to morbidity and mortality. In this article, we extend this parameter to the attributable fraction function in survival analysis of time-to-event outcomes, and further establish its estimation and inference procedures based on the widely used proportional hazards models. Numerical examples and simulations studies are presented to validate and demonstrate the proposed methods.
Epidemiology | Survival Analysis
Chen, Ying Qing; Hu, Chengcheng; and Wang, Yan, "Attributable Risk Function in the Proportional Hazards Model" (May 2005). UW Biostatistics Working Paper Series. Working Paper 254.