Abstract
Partial least squares (PLS), which is an unsupervised dimensionality reduction method, has been widely used in metabolomics. PLS can separate score depend on groups in a low dimensional subspace. However, this cannot use the information about rank order of groups. This information is often provided in which concentration of administered drugs to animals is gradually varies. In this study, we proposed partial least squares for rank order of groups (PLS-ROG). PLS-ROG can consider both separation and rank order of groups.
Disciplines
Biostatistics
Suggested Citation
Yamamoto, Hiroyuki, "PLS-ROG: Partial least squares with rank order of groups" (October 2012). COBRA Preprint Series. Working Paper 100.
https://biostats.bepress.com/cobra/art100