COBRA Preprint Series
The COBRA Preprint Series contains manuscripts by top researchers, many of which will eventually appear in leading journals. For a look ahead to tomorrow's cutting edge research, browse the papers below.
Search Collection of Biostatistics Research Archive
- Papers from 2009
- Mean Survival Time from Right Censored Data (December 15, 2009)
Download PDF [989 K] Summary - Targeted Genomic signature profiling with Quasi-alignment statistics (November 17, 2009)
Download PDF [2.8 MB] Summary - Two-stage Decompositions for the Analysis of Functional Connectivity for fMRI With Application to Alzheimer's Disease Risk (November 14, 2009)
Download PDF [6.1 MB] Summary - Modeling Multilevel Sleep Transitional Data Via Poisson Log-Linear Multilevel Models (October 18, 2009)
Download PDF [1.6 MB] Summary - Composite Likelihood EM Algorithm with Applications to Multivariate Hidden Markov Model (September 30, 2009)
Download PDF [837 K] Summary - Shrinkage Estimation of Expression Fold Change As an Alternative to Testing Hypotheses of Equivalent Expression (August 10, 2009)
Download PDF [2.1 MB] Summary - Reliability of the Model for Clustering of Longitudinal datasets of Infant Mortality Rate in India (July 15, 2009)
Download PDF [763 K] Summary - Simple, Defensible Sample Sizes Based on Cost Efficiency -- With Discussion and Rejoinder (June 12, 2009)
Download PDF [1.4 MB] Summary - Nonparametric Incidence Estimation From Prevalent Cohort Survival Data (March 31, 2009)
Download PDF [1.4 MB] Summary - A Novel Topology for Representing Protein Folds (March 24, 2009)
Download PDF [2.1 MB] Summary - Fitting ACE Structural Equation Models to Case-Control Family Data (March 18, 2009)
Download PDF [1.2 MB] Summary - Correlated Binary Regression Using Orthogonalized Residuals (March 10, 2009)
Download PDF [692 K] Summary - Validation of Differential Gene Expression Algorithms: Application Comparing Fold Change Estimation to Hypothesis Testing (February 13, 2009)
Download PDF [1016 K] Summary - Papers from 2008
- Space-Time Regression Modeling of Tree Growth Using the Skew-t Distribution (December 1, 2008)
Download PDF [2.5 MB] Summary - Detection of Recurrent Copy Number Alterations in the Genome: a Probabilistic Approach (November 20, 2008)
Download PDF [1.5 MB] Summary - Reversal in declining trend of adult mortality in many states of India, 1970-2001: Is it due to AIDS? (November 19, 2008)
Download PDF [477 K] Summary - Finding Recurrent Regions of Copy Number Variation: A Review (November 18, 2008)
Download PDF [1.3 MB] Summary - Change-point Problem and Regression: An Annotated Bibliography (November 12, 2008)
Download PDF [7.7 MB] Summary - A SIMPLE INDEX OF SMOKING (November 6, 2008)
Download PDF [2.1 MB] Summary - The Strength of Statistical Evidence for Composite Hypotheses with an Application to Multiple Comparisons (November 3, 2008)
Download PDF [1.5 MB] Summary - A New Method for Constructing Exact Tests without Making any Assumptions (August 23, 2008)
Download PDF [1.2 MB] Summary - Properties of Monotonic Effects on Directed Acyclic Graphs (August 7, 2008)
Download PDF [684 K] Summary - Joint Spatial Modeling of Recurrent Infection and Growth with Processes Under Intermittent Observation (August 1, 2008)
Download PDF [1.8 MB] Summary - The Calculation of the 97.5% Upper Confidence Bound: Application to Clustered Binary Data in a Binomial Non-Inferiority Two-Sample Trial. (July 11, 2008)
Download PDF [555 K] Summary - The Design and Sample Size Requirement for a Cluster Randomized Non-Inferiority Trial with Two Binary Co-Primary Outcomes. (July 11, 2008)
Download PDF [605 K] Summary - Bringing Game Theory to Hypothesis Testing: Establishing Finite Sample Bounds on Inference (June 25, 2008)
Download PDF [1.1 MB] Summary - Properties of Monotonic Effects on Directed Acyclic Graphs (April 15, 2008)
Download PDF [685 K] Summary - Papers from 2007
- Estimation of Dose-Response Functions for Longitudinal Data (November 13, 2007)
Download PDF [1.1 MB] Summary - Bootstrap Confidence Regions for Optimal Operating Conditions in Response Surface Methodology (November 12, 2007)
Download PDF [876 K] Summary - Estimating the Prevalence of Disease Using Relatives of Case and Control Probands (August 6, 2007)
Download PDF [1.2 MB] Summary - An Example of How to Write the Statistical Section of a Bioequivalence Study Protocol for FDA Review (July 25, 2007)
Download PDF [535 K] Summary - Adjustment to the McNemar’s Test for the Analysis of Clustered Matched-Pair Data (July 17, 2007)
Download PDF [298 K] Summary - Assessment of Sample Size and Power for the Analysis of Clustered Matched-Pair Data (July 17, 2007)
Download PDF [193 K] Summary - Lachenbruch’s Method for Determining the Sample Size Required for Testing Interactions: How It Compares to nQuery Advisor and O’Brien’s SAS UnifyPow. (July 16, 2007)
Download PDF [195 K] Summary - The Existence of Maximum Likelihood Estimates for the Binary Response Logistic Regression Model (July 16, 2007)
Download PDF [527 K] Summary - The Assessment of the Degree of Concordance Between the Observed Values and the Predicted Values of a Mixed-Effect Model Using “Method of Comparison” Techniques (July 12, 2007)
Download PDF [1.7 MB] Summary - The Analysis of Pixel Intensity (Myocardial Signal Density) Data: The Quantification of Myocardial Perfusion by Imaging Methods. (May 21, 2007)
Download PDF [604 K] Summary - Coronary Evaluation Using Multi-detector Spiral Computed Tomography Angiography: Statistical Design and Analysis (May 21, 2007)
Download PDF [529 K] Summary - Review of the Maximum Likelihood Functions for Right Censored Data. A New Elementary Derivation. (May 3, 2007)
Download PDF [500 K] Summary - A Flexible Semi-Parametric Approach to Estimating a Dose-Response Relationship: the Treatment of Childhood Amblyopia. (March 29, 2007)
Download PDF [1.0 MB] Summary - False Discovery Rate Analysis of Brain Diffusion Direction Maps (March 28, 2007)
Download PDF [1.2 MB] Summary - A Bayesian hierarchical model for spot fluorescence in microarrays (March 28, 2007)
Download PDF [951 K] Summary - Improving GSEA for Analysis of Biologic Pathways for Differential Gene Expression across a Binary Phenotype (January 7, 2007)
Download PDF [663 K] Summary - Papers from 2006
- Properties of Monotonic Effects (November 8, 2006)
Download PDF [531 K] Summary - Exploration of distributional models for a novel intensity-dependent normalization (October 12, 2006)
Download PDF [2.1 MB] Summary - Crude Cumulative Incidence in the form of a Horvitz-Thompson like and Kaplan-Meier like Estimator (October 2, 2006)
Download PDF [538 K] Summary - A Theory of Sufficient Cause Interactions (September 27, 2006)
Download PDF [784 K] Summary - Biologic Interaction and Their Identification (September 27, 2006)
Download PDF [555 K] Summary - A unifying approach for haplotype analysis of quantitative traits in family-based association studies: Testing and estimating gene-environment interactions with complex exposure variables (September 6, 2006)
Download PDF [1.3 MB] Summary - A Flexible Statistical Method for Detecting Genomic Copy-Number Changes Using Hidden Markov Models with Reversible Jump MCMC (August 24, 2006)
Download PDF [1.3 MB] Summary - Survival Analysis of Longitudinal Microarrays (July 24, 2006)
Download PDF [960 K] Summary - Causal Comparisons in Randomized Trials of Two Active Treatments: The Effect of Supervised Exercise to Promote Smoking Cessation (July 3, 2006)
Download PDF [1.2 MB] Summary - New Spiked-In Probe Sets for the Affymetrix HGU-133A Latin Square Experiment (June 10, 2006)
Download PDF [1.0 MB] Summary - Simple Records Matching Method for diagnostic and clinical datasets of patient’s records (April 11, 2006)
Download PDF [738 K] Summary - Papers from 2005
- Sample size and power calculations for body weight in beef cattle (August 29, 2005)
Download PDF [550 K] Summary - New Statistical Paradigms Leading to Web-Based Tools for Clinical/Translational Science (May 23, 2005)
Download PDF [2.5 MB] Summary