The Department of Biostatistics is one of 5 departments in the School of Public Health and Community Medicine at the University of Washington. Its mission is to serve as a source of expertise and a focus for training and research in the quantitative aspects of public health and medicine, and to promote the use of rigorous quantitative methods in the biomedical and public health sciences.

Our graduate program is regarded as one of the best Biostatistics programs in the world, with over 30 years of teaching and research experience on the UW campus. Faculty interests range over a wide variety of statistical topics, including survival analysis, clinical trials, statistical genetics and correlated data.

The UW Biostatistics Working Paper series includes articles on statistical methods and applications developed by members of the department. In general, articles dated 2000 and later are downloadable from this site.

Submission Guidelines.
Please follow the Policies and Procedures page for submission guidelines.

Follow

Papers from 2003

PDF

Estimating Disease Prevalence in Two-Phase Studies, Todd A. Alonzo and Margaret S. Pepe

PDF

Whither PQL?, Norm Breslow

PDF

Constrained Boundary Monitoring for Group Sequential Clinical Trials, Bart E. Burington and Scott S. Emerson

PDF

Semiparametric Receiver Operating Characteristic Analysis to Evaluate Biomarkers for Disease, Tianxi Cai and Margaret S. Pepe

PDF

The Sensitivity and Specificity of Markers for Event Times, Tianxi Cai, Margaret S. Pepe, Thomas Lumley, Yingye Zheng, and Nancy Swords Jenny

PDF

Partial AUC Estimation and Regression, Lori E. Dodd and Margaret S. Pepe

PDF

Semi-parametric Regression for the Area Under the Receiver Operating Characteristic Curve, Lori E. Dodd and Margaret S. Pepe

PDF

Sensitivity Analysis for the Assessment of Causal Vaccine Effects on Viral Load in HIV Vaccine Trials, Peter B. Gilbert, Ronald J. Bosch, and Michael G. Hudgens

PDF

Tests for Comparing Mark-Specific Hazards and Cumulative Incidence Functions, Peter B. Gilbert, Ian W. McKeague, and Yanqing Sun

PDF

Survival Model Predictive Accuracy and ROC Curves, Patrick Heagerty and Yingye Zheng

PDF

Design of the HIV Prevention Trials Network (HPTN) Protocol 054: A cluster randomized crossover trial to evaluate combined access to Nevirapine in developing countries, Jim Hughes, Robert L. Goldenberg, Catherine M. Wilfert, Megan Valentine, Kasonde G. Mwinga, Laura A. Guay, Francis Mmiro, and Jeffrey S. A. Stringer

PDF

Estimating the accuracy of polymerase chain reaction-based tests using endpoint dilution, Jim Hughes and Patricia Totten

PDF

Identifying Target Populations for Screening or Not Screening Using Logic Regression, Holly Janes, Margaret S. Pepe, Charles Kooperberg, and Polly Newcomb

PDF

Bootstrap Confidence Intervals for Medical Costs With Censored Observations, Hongyu Jiang and Xiao-Hua Zhou

PDF

Design Considerations for Efficient and Effective Microarray Studies, M. Kathleen Kerr

PDF

Linear Models for Microarray Data Analysis: Hidden Similarities and Differences, M. Kathleen Kerr

PDF

Marginalized Transition Models for Longitudinal Binary Data With Ignorable and Nonignorable Dropout, Brenda F. Kurland and Patrick J. Heagerty

PDF

Asymptotics for Marginal Generalized Linear Models With Sparse Correlations, Thomas Lumley and Nicole Mayer Hamblett

PDF

Marginal Modeling of Multilevel Binary Data with Time-Varying Covariates, Diana Miglioretti and Patrick Heagerty

PDF

Selecting Differentially Expressed Genes from Microarray Experiments, Margaret S. Pepe, Gary M. Longton, Garnet L. Anderson, and Michel Schummer

Modeling Breastmilk Infectivity in HIV-1 Infected Mothers, Barbra A. Richardson and James P. Hughes

PDF

Literate Statistical Practice, Anthony Rossini and Friedrich Leisch

PDF

Simple Parallel Statistical Computing in R, Anthony Rossini, Luke Tierney, and Na Li

PDF

A Corrected Pseudo-score Approach for Additive Hazards Model With Longitudinal Covariates Measured With Error, Xiao Song and Yijian Huang

PDF

A Bootstrap Confidence Interval Procedure for the Treatment Effect Using Propensity Score Subclassification, Wanzhu Tu and Xiao-Hua Zhou

PDF

Partly Conditional Survival Models for Longitudinal Data, Yingye Zheng and Patrick Heagerty

PDF

Semiparametric Estimation of Time-Dependent: ROC Curves for Longitudinal Marker Data, Yingye Zheng and Patrick Heagerty

PDF

Adjusting for Non-Ignorable Verification Bias in Clinical Studies for Alzheimer’s Disease, Xiao-Hua Zhou and Pete Castelluccio

PDF

A New Confidence Interval for the Difference Between Two Binomial Proportions of Paired Data, Xiao-Hua Zhou and Gengsheng Qin

PDF

Improved Confidence Intervals for the Sensitivity at a Fixed Level of Specificity of a Continuous-Scale Diagnostic Test, Xiao-Hua Zhou and Gengsheng Qin

PDF

New Intervals for the Difference Between Two Independent Binomial Proportions, Xiao-Hua Zhou, Min Tsao, and Gengsheng Qin

Papers from 2002

PDF

Large Sample Theory for Semiparametric Regression Models with Two-Phase, Outcome Dependent Sampling, Norm Breslow, Brad McNeney, and Jon A. Wellner

PDF

Performance of the Halex in Logitudinal Studies of Older Adults, Paula Diehr, Donald L. Patrick, Gregory L. Burke, and Jeff D. Williamson

PDF

The Analysis of Placement Values for Evaluating Discriminatory Measures, Margaret S. Pepe and Tianxi Cai

A Data-Analytic Strategy for Protein-Biomarker Discovery: Profiling of High-Dimensional Proteomic Data for Cancer Detection, Yutaka Yasui, Margaret S. Pepe, Mary Lou Thompson, Bao-Ling Adam, George L. Wright Jr., Yinsheng Qu, John D. Potter, Marcy Winget, Mark Thornquist, and Ziding Feng

Papers from 2001

PDF

Probabilities of Transition Among Health States for Older Adults, Paula Diehr and Donald L. Patrick

PDF

Emacs Speaks Statistics: A Universal Interface for Statistical Analysis, Anthony Rossini, Martin Maechler, Kurt Hornik, Richard M. Heiberger, and Rodney Sparapani

Papers from 1998

PDF

Assessing the Accuracy of a New Diagnostic Test When a Gold Standard Does Not Exist, Todd A. Alonzo and Margaret S. Pepe

Selection of Matching Variables in Community Health Intervention Trials, Andrew J. Dunning

Papers from 1997

PDF

Pooling Community Data for Community Interventions When the Number of Pairs is Small, Paula Diehr, Ted Lystig, Holly Andrilla, and Ziding Feng

PDF

Multiple Outcomes in Health Services Research: Hypothesis Tests and Power, Donald C. Martin, Paula Diehr, Thomas D. Koepsell, and Stephan D. Fihn

Papers from 1994

PDF

An Empirical Study of Small-Area Variation for ICD-9 Surgical Procedures, Paula Diehr, Kevin Cain, Zhan Ye, and John Loeser

Papers from 1993

PDF

Breaking the Matches in a Paired T-Test for Community Interventions When the Number of Pairs is Small, Paula Diehr, Don C. Martin, Thomas D. Koepsell, and Allen D. Cheadle

Papers from 1992

PDF

The Multiple Admission Factor (MAF) in Small Area Variation Analysis, Kevin Cain and Paula Diehr

Papers from 1989

PDF

Regression Models for Bivariate Binary Responses, Juni Palmgren

Papers from 1980

PDF

Sample Size Calculations and Optimal Followup Time in Health Services Research Using Utilization Rates, Paula Diehr

Papers from 1978

PDF

Statistical Measures for Admission Rates, Paula Diehr