The Department of Biostatistics is one of 5 departments in the School of Public Health and Community Medicine at the University of Washington. Its mission is to serve as a source of expertise and a focus for training and research in the quantitative aspects of public health and medicine, and to promote the use of rigorous quantitative methods in the biomedical and public health sciences.
Our graduate program is regarded as one of the best Biostatistics programs in the world, with over 30 years of teaching and research experience on the UW campus. Faculty interests range over a wide variety of statistical topics, including survival analysis, clinical trials, statistical genetics and correlated data.
The UW Biostatistics Working Paper series includes articles on statistical methods and applications developed by members of the department. In general, articles dated 2000 and later are downloadable from this site.
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Please follow the Policies and Procedures page for submission guidelines.
Papers from 2003
Estimating Disease Prevalence in Two-Phase Studies, Todd A. Alonzo and Margaret S. Pepe
Whither PQL?, Norm Breslow
Constrained Boundary Monitoring for Group Sequential Clinical Trials, Bart E. Burington and Scott S. Emerson
Semiparametric Receiver Operating Characteristic Analysis to Evaluate Biomarkers for Disease, Tianxi Cai and Margaret S. Pepe
The Sensitivity and Specificity of Markers for Event Times, Tianxi Cai, Margaret S. Pepe, Thomas Lumley, Yingye Zheng, and Nancy Swords Jenny
Partial AUC Estimation and Regression, Lori E. Dodd and Margaret S. Pepe
Semi-parametric Regression for the Area Under the Receiver Operating Characteristic Curve, Lori E. Dodd and Margaret S. Pepe
Sensitivity Analysis for the Assessment of Causal Vaccine Effects on Viral Load in HIV Vaccine Trials, Peter B. Gilbert, Ronald J. Bosch, and Michael G. Hudgens
Tests for Comparing Mark-Specific Hazards and Cumulative Incidence Functions, Peter B. Gilbert, Ian W. McKeague, and Yanqing Sun
Survival Model Predictive Accuracy and ROC Curves, Patrick Heagerty and Yingye Zheng
Design of the HIV Prevention Trials Network (HPTN) Protocol 054: A cluster randomized crossover trial to evaluate combined access to Nevirapine in developing countries, Jim Hughes, Robert L. Goldenberg, Catherine M. Wilfert, Megan Valentine, Kasonde G. Mwinga, Laura A. Guay, Francis Mmiro, and Jeffrey S. A. Stringer
Estimating the accuracy of polymerase chain reaction-based tests using endpoint dilution, Jim Hughes and Patricia Totten
Identifying Target Populations for Screening or Not Screening Using Logic Regression, Holly Janes, Margaret S. Pepe, Charles Kooperberg, and Polly Newcomb
Bootstrap Confidence Intervals for Medical Costs With Censored Observations, Hongyu Jiang and Xiao-Hua Zhou
Design Considerations for Efficient and Effective Microarray Studies, M. Kathleen Kerr
Linear Models for Microarray Data Analysis: Hidden Similarities and Differences, M. Kathleen Kerr
Marginalized Transition Models for Longitudinal Binary Data With Ignorable and Nonignorable Dropout, Brenda F. Kurland and Patrick J. Heagerty
Asymptotics for Marginal Generalized Linear Models With Sparse Correlations, Thomas Lumley and Nicole Mayer Hamblett
Marginal Modeling of Multilevel Binary Data with Time-Varying Covariates, Diana Miglioretti and Patrick Heagerty
Selecting Differentially Expressed Genes from Microarray Experiments, Margaret S. Pepe, Gary M. Longton, Garnet L. Anderson, and Michel Schummer
Modeling Breastmilk Infectivity in HIV-1 Infected Mothers, Barbra A. Richardson and James P. Hughes
Literate Statistical Practice, Anthony Rossini and Friedrich Leisch
Simple Parallel Statistical Computing in R, Anthony Rossini, Luke Tierney, and Na Li
A Corrected Pseudo-score Approach for Additive Hazards Model With Longitudinal Covariates Measured With Error, Xiao Song and Yijian Huang
A Bootstrap Confidence Interval Procedure for the Treatment Effect Using Propensity Score Subclassification, Wanzhu Tu and Xiao-Hua Zhou
Partly Conditional Survival Models for Longitudinal Data, Yingye Zheng and Patrick Heagerty
Semiparametric Estimation of Time-Dependent: ROC Curves for Longitudinal Marker Data, Yingye Zheng and Patrick Heagerty
Adjusting for Non-Ignorable Verification Bias in Clinical Studies for Alzheimer’s Disease, Xiao-Hua Zhou and Pete Castelluccio
A New Confidence Interval for the Difference Between Two Binomial Proportions of Paired Data, Xiao-Hua Zhou and Gengsheng Qin
Improved Confidence Intervals for the Sensitivity at a Fixed Level of Specificity of a Continuous-Scale Diagnostic Test, Xiao-Hua Zhou and Gengsheng Qin
New Intervals for the Difference Between Two Independent Binomial Proportions, Xiao-Hua Zhou, Min Tsao, and Gengsheng Qin
Papers from 2002
Large Sample Theory for Semiparametric Regression Models with Two-Phase, Outcome Dependent Sampling, Norm Breslow, Brad McNeney, and Jon A. Wellner
Performance of the Halex in Logitudinal Studies of Older Adults, Paula Diehr, Donald L. Patrick, Gregory L. Burke, and Jeff D. Williamson
The Analysis of Placement Values for Evaluating Discriminatory Measures, Margaret S. Pepe and Tianxi Cai
A Data-Analytic Strategy for Protein-Biomarker Discovery: Profiling of High-Dimensional Proteomic Data for Cancer Detection, Yutaka Yasui, Margaret S. Pepe, Mary Lou Thompson, Bao-Ling Adam, George L. Wright Jr., Yinsheng Qu, John D. Potter, Marcy Winget, Mark Thornquist, and Ziding Feng
Papers from 2001
Probabilities of Transition Among Health States for Older Adults, Paula Diehr and Donald L. Patrick
Emacs Speaks Statistics: A Universal Interface for Statistical Analysis, Anthony Rossini, Martin Maechler, Kurt Hornik, Richard M. Heiberger, and Rodney Sparapani
Papers from 1998
Assessing the Accuracy of a New Diagnostic Test When a Gold Standard Does Not Exist, Todd A. Alonzo and Margaret S. Pepe
Selection of Matching Variables in Community Health Intervention Trials, Andrew J. Dunning
Papers from 1997
Pooling Community Data for Community Interventions When the Number of Pairs is Small, Paula Diehr, Ted Lystig, Holly Andrilla, and Ziding Feng
Multiple Outcomes in Health Services Research: Hypothesis Tests and Power, Donald C. Martin, Paula Diehr, Thomas D. Koepsell, and Stephan D. Fihn
Papers from 1994
An Empirical Study of Small-Area Variation for ICD-9 Surgical Procedures, Paula Diehr, Kevin Cain, Zhan Ye, and John Loeser
Papers from 1993
Breaking the Matches in a Paired T-Test for Community Interventions When the Number of Pairs is Small, Paula Diehr, Don C. Martin, Thomas D. Koepsell, and Allen D. Cheadle
Papers from 1992
The Multiple Admission Factor (MAF) in Small Area Variation Analysis, Kevin Cain and Paula Diehr
Papers from 1989
Regression Models for Bivariate Binary Responses, Juni Palmgren
Papers from 1980
Sample Size Calculations and Optimal Followup Time in Health Services Research Using Utilization Rates, Paula Diehr
Papers from 1978
Statistical Measures for Admission Rates, Paula Diehr